Notice on Further Strengthening Drug Safety Management and Improving the Level of Reasonable Drug Use

Guo Wei Yi Han[2022]No.122

To the health committees and bureaus of traditional Chinese medicine of all provinces,autonomous regions,municipalities directly under the Central Government and the Xinjiang Production and Construction Corps:

In order to further strengthen the management of medication safety,improve the level of rational medication,and ensure the quality and safety of medical treatment and the rights and interests of people's health,the following work requirements are proposed.

1、Reduce the risk of medication errors and improve the level of medication safety

（1）Strengthen the implementation of medication safety systems.Medical institutions should improve and implement medication safety related systems,enhance the awareness and ability of medical and technical personnel to prevent medication errors,and implement the full process management of prescription issuance,dispensing,administration,and medication.Physicians should provide correct,standardized,and appropriate prescriptions based on the patient's condition;The pharmacist carefully performs the responsibility of prescription review,and all prescriptions and medication orders are dispensed after being reviewed as qualified;Nurses and other medical personnel who execute medication orders should carefully verify and strictly follow the"three checks and seven checks"to ensure the accuracy of the time,route,dosage,and other aspects of medication administration.Encourage medical institutions to use information technology to intelligently review and manage the entire process of clinical medication.

（2）Strengthen the management of key drug use.Medical institutions should establish a management system for high warning drugs and easily confused drugs,and store and set warning signs for high warning drugs and multiple specifications,appearance,and sound of easily confused drugs within their own institutions.Strengthen the training of various departments and medical personnel to enable them to accurately identify;During the handover and distribution of drugs,medical personnel should remind each other,provide medication education to patients,and pay attention to preventing misselection and misuse.At the same time,we will strengthen the monitoring and management of the use of drugs for rational drug use,antimicrobial drugs,anti-tumor drugs,proton pump inhibitors,glucocorticoids,toxic drugs,and traditional Chinese medicine injections.Through blood drug concentration monitoring,Genetic testing,etc.,identify drug risks,develop individualized drug use plans,optimize drug variety selection,and accurately determine drug dosage.

（3）Ensure the safety of medication for key populations.Medical institutions should strengthen drug safety management for special populations such as the elderly,children,and pregnant women.Establish a medication management system for elderly patients,adopt graded management measures for elderly patients with different risk levels,strengthen medication disclosure and reminders,and avoid using the wrong medication.When selecting drugs for children(only those drugs whose indications for children and usage and dosage for children are specified in the Medication package insert),they may not be restricted by the"one product,two regulations"and the total number of drugs,increase the scope of drug use and promote accurate drug use.According to the characteristics of pregnant and lying in women,it is necessary to strengthen the management of all links of rational drug use,focus on the prohibition and caution of drug use for pregnant and lying in women,strive to achieve"the minimum Effective dose,the shortest effective course of treatment,and the minimum toxic and side effects",and minimize the impact on pregnant and lying in women and the fetus.

2、Strengthen monitoring reports and analysis,actively respond to adverse drug reactions

（4）Prepare adverse drug reaction monitoring reports.Medical institutions should monitor and report adverse drug reactions in accordance with regulations,actively collect adverse drug reactions,and report relevant information to relevant departments in a timely manner according to the principle of"reporting suspicious cases",in order to improve the quantity and quality of reports.Establish and maintain adverse drug reaction reports and monitoring files,and ensure the safety and safety of patients with multiple adverse reactions.